- Original Article
- Alteration of CD4+CD25+Foxp3+ T cell level in Kawasaki disease
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Su Ye Sohn, Young Wooh Song, Yun Ku Yeo, Yun Kyung Kim, Gi Young Jang, Chan Wook Woo, Jung Hwa Lee, Kwang Chul Lee
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Clin Exp Pediatr. 2011;54(4):157-162. Published online April 30, 2011
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Purpose Exaggerated pro-inflammatory reactions during the acute phase of Kawasaki disease (KD) suggest the role of immune dysregulation in the pathogenesis of KD. We investigated the profiles of T regulatory cells and their correlation with the clinical course of KD. MethodsPeripheral blood mononuclear cells were collected from 17 KD patients during acute febrile and subacute afebrile phases. T cells expressing CD4, CD25,... |
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